The lethal dose of a drug can vary among individuals.
What Factors Can Affect The Lethal Dose Of Ketamine? The lethal dose of ketamine is approximately 25 times the standard recreational dose.ĭeath from ketamine has also been reported after administering 10 times the standard dose for medical anesthesia. 450 to 750 milligrams (mg) for medical anesthesia.The lethal dose of ketamine is estimated to be about 4.2 grams, or 4,200 milligrams for a 154-pound human. How A Lethal Dose Of Ketamine Is Determined Learn more about the lethal doses of commonly abused drugs. Taking excessive doses of ketamine, or mixing it with other drugs, can have toxic effects, including fatal respiratory depression. When used recreationally, it is most commonly snorted or injected.įatal ketamine overdose is uncommon, but it can occur. It is sometimes used recreationally for its hallucinogenic effects. Extremely high doses of ketamine can have life-threatening consequences when taken alone or with other drugs. Ketamine is a strong anesthetic drug that can have hallucinogenic effects.